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supplement

Horny Goat Weed

Also known as: Epimedium, Icariin

Evidence: High · 90%
Half-life
6 h
Typical timing
any
Food rule
either
Default unit
—

Studied for

libidoperformance

Overview

A family of flavonoid-rich botanicals used for centuries in TCM for sexual function and bone health. The primary active is icariin.

Deep dive

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Known interactions

  • Category rule: glp1 × supplement
    Note

    GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.

    Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

Frequently asked

Sources referenced

- Dell'Agli M et al. Potent inhibition of human PDE5 by icariin derivatives. J Nat Prod 2008.\n- Ma H et al. The genus Epimedium: an ethnopharmacological and phytochemical review. J Ethnopharmacol 2011.

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Horny Goat Weed — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/horny-goat-weed
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Related compounds

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Related benefits

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libido

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