supplement

Stinging Nettle Root

Also known as: Urtica dioica

Evidence: High · 90%
Half-life
8 h
Typical timing
any
Food rule
either
Default unit

Studied for

Overview

Root of Urtica dioica, distinct from the leaf (which is used for allergies and inflammation). Common in European BPH formulas and men's testosterone stacks.

Deep dive

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Known interactions

  • Category rule: glp1 × supplement
    Note

    GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.

    Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

Frequently asked

Sources referenced

- Safarinejad MR. Urtica dioica for BPH: a double-blind trial. J Herb Pharmacother 2005.\n- Schöttner M et al. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin. Planta Med 1997.

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Stinging Nettle Root — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/stinging-nettle-root
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