hormoneInjectableControlledSchedule III (US)Not FDA-approvedApproved only as a veterinary anabolic (Equipoise) for animals, never for human useHuman literature is limited to forensic detection and animal-model toxicology; no published human dosing trial

Boldenone UndecylenateBenefits, Dosage & Interactions

Also known as: Equipoise, EQ

Boldenone undecylenate is an injectable anabolic-androgenic steroid developed for veterinary use, best known under the brand name Equipoise. The long undecylenate ester releases boldenone slowly, giving an elimination half-life measured in weeks and detection windows of several months. Research on Boldenone Undecylenate focuses on muscle and strength and endurance.

Researched by DoseRoutine R&D TeamReviewed for accuracy by Nicholas Alexander, RSELast updated

Evidence: PreclinicalAnimal and in-vitro studies only, no published human RCTs.
Evidence strengthPreclinical · 1/4
PreclinicalStrong human evidence

Animal and in-vitro studies only, no published human RCTs.

Chemical structure of Boldenone Undecylenate (PubChem CID 11954310)
Structure via PubChem

Quick answer

Boldenone undecylenate is an injectable anabolic-androgenic steroid developed for veterinary use, best known under the brand name Equipoise. The long undecylenate ester releases boldenone slowly, giving an elimination half-life measured in weeks and detection windows of several months. It has no approved human medical use in the United States, is a Schedule III controlled substance, and is prohibited in sport by WADA. Documented risks mirror other AAS: suppressed natural testosterone, adverse lipid shifts, raised hematocrit and cardiovascular strain.

Brand name
Equipoise (veterinary)
Class
Injectable anabolic-androgenic steroid (testosterone derivative)
Ester
Undecylenate — slow release, long-acting
Half-life
Roughly 14 days; detectable for months
Legal status
DEA Schedule III in the U.S.; no approved human use
Sport status
Prohibited at all times under the WADA code

Compiled by DoseRoutine from public sources including NIH/MedlinePlus, the FDA label, Mayo Clinic and PubChem. Educational information, not medical advice.

Plasma half-life
Not established
Default unit
mg

References & evidence

Documents the Boldenone Undecylenate entry is written from. Each number matches an inline marker above.

  1. [1]Ginseng nanoparticles mitigate boldenone-induced testicular oxidative damage and reproductive dysfunction in adult male ratsAli FAZ, Hassan H, Hamed AM, et al. · Tissue & Cell · 2026 · Peer-reviewed · PMID 41990696
  2. [2]Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino ratsMowaad NA, Asaad GF, El-Shamarka MEA, Khalil S · Iranian Journal of Basic Medical Sciences · 2022 · Peer-reviewed · PMID 36033952

How to track Boldenone Undecylenate doses

Boldenone Undecylenate is tracked as a protocol rather than a single reminder: a vial with a concentration, a schedule that may be titrated or cycled, and a rotation of injection sites. Here is the record that keeps all three consistent.

  1. 1

    Record the vial and concentration

    Log the vial strength and the volume of bacteriostatic water you added so Boldenone Undecylenate is stored as a concentration rather than a guess. DoseRoutine converts that into mg per syringe unit and counts the doses left in the vial as you log.

  2. 2

    Set the schedule, not just a reminder

    Enter the dose in mg and the frequency. Cycled protocols get a start and end date so the history stays accurate when Boldenone Undecylenate comes out of the routine.

  3. 3

    Rotate and log the injection site

    Pick the site at the moment you log the dose. The site map shows what you used last and how recently, which is the part that drifts fastest when two compounds run on different frequencies.

  4. 4

    Log adherence, not intentions

    Mark each dose taken, skipped or delayed as it happens. Weeks of honest logs are what make an adherence rate or a trend line meaningful; retrospective guessing is not.

  5. 5

    Review against outcomes

    Review Boldenone Undecylenate alongside your logged metrics and any relevant blood work every few weeks before changing the dose, so the change is a response to data rather than to a good or bad day.

What to log each time

  • Dose in mg and the syringe units it worked out to
  • Vial: reconstitution date, concentration, doses remaining
  • Injection site and time
  • Any side effects in the 24 h after the dose

References & Evidence

Sources on this page that document Boldenone Undecylenate dosing, timing and safety.

  1. [1]National Center for Biotechnology Information View source

Educational information only — not medical advice. Dose ranges vary by person, indication and prescriber.

What is Boldenone Undecylenate studied for?

What is Boldenone Undecylenate?Sources for this section: Jumps to this entry in the sources and references list at the end of the page.

Boldenone Undecylenate, often known by its trade name Equipoise or its common abbreviation EQ, is a synthetic anabolic androgenic steroid (AAS) derived from testosterone. It is structurally similar to testosterone but with a double bond at the 1-position. This structural modification is intended to reduce its androgenic effects while retaining anabolic properties. Boldenone Undecylenate is the undecylenate ester of boldenone, which means a long ester chain is attached to prolong its release and activity in the body after injection. In veterinary medicine, it has been used to promote lean muscle mass, appetite, and red blood cell production in horses and other animals. In human contexts, though not approved for human use by regulatory bodies like the U.S. Food and Drug Administration (FDA), it is sometimes used illicitly for performance enhancement, particularly in bodybuilding and athletics, with the aim of increasing muscle mass, strength, and endurance. Due to its long ester, Boldenone Undecylenate has a prolonged release profile, leading to sustained blood levels and requiring less frequent injections compared to shorter-esterified compounds. The effects are generally considered to be slower and more gradual compared to some other anabolic steroids, often leading to more qualitative and sustainable gains in muscle mass over extended periods rather than rapid, dramatic increases in weight. The use of this compound carries significant health risks and is restricted, being a Schedule III controlled substance in the United States due to its potential for abuse and adverse effects. This information is derived from sources like DrugBank and relevant regulatory guidelines. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

What does the research say about Boldenone Undecylenate?

Tap a section to expand.

As an anabolic androgenic steroid, Boldenone Undecylenate exerts its effects primarily by binding to androgen receptors located in various tissues throughout the body, including skeletal muscle, bone, and reproductive tissues. This binding initiates a cascade of genetic and cellular events. Upon binding to the androgen receptor, the steroid-receptor complex translocates into the cell nucleus, where it can interact with specific DNA sequences (androgen response elements) to modulate gene transcription. This leads to altered protein synthesis, particularly increasing nitrogen retention and protein synthesis in muscle cells, which are key processes for muscle growth (anabolism). Additionally, Boldenone Undecylenate is known to stimulate erythropoiesis, the production of red blood cells, in the kidneys. This effect is mediated by increasing the production of erythropoietin, a hormone that promotes red blood cell formation. Increased red blood cell count can enhance oxygen-carrying capacity, potentially improving endurance and reducing fatigue during physical activity. Although Boldenone is structurally related to testosterone, its double bond at the 1-position reduces its tendency to aromatize into estrogens. Aromatization is the process by which some androgens are converted into estrogens by the aromatase enzyme. While boldenone does undergo some aromatization, it is generally considered to be at a lower rate than an equivalent dose of testosterone, potentially leading to fewer estrogen-related side effects such as gynecomastia and water retention. The undecylenate ester attached to boldenone is a long chain that prolongs the release of the active hormone into the bloodstream after intramuscular injection. This esterification means the compound is slowly cleaved from the boldenone molecule by esterase enzymes in the body, resulting in a sustained and steady release over several weeks. This mechanism of action is consistent with information found in pharmacological databases like DrugBank. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Source for this section: Sources for How does Boldenone Undecylenate work?: Jumps to this entry in the sources and references list at the end of the page.

In contexts of illicit use by athletes and bodybuilders, the perceived benefits of Boldenone Undecylenate are largely centered around its anabolic properties. Users might seek increases in lean muscle mass, as the compound promotes protein synthesis and nitrogen retention within muscle cells. This is often described as a more qualitative gain compared to some other steroids, meaning slower but potentially more sustainable and higher quality muscle tissue growth without excessive water retention. Another commonly reported benefit in non-medical use is an increase in appetite, which can be advantageous for individuals struggling to consume sufficient calories for muscle growth. Furthermore, due to its ability to stimulate erythropoiesis (red blood cell production), users may experience enhanced endurance and stamina. A greater red blood cell count improves oxygen delivery to muscles, which can delay fatigue during prolonged physical exertion. The relatively lower rate of aromatization compared to some other steroids is also attractive, as it may reduce the incidence of estrogen-related side effects like gynecomastia (enlargement of male breast tissue) and significant water retention. This contributes to a 'harder' and more defined muscular appearance. However, it is crucial to note that these mentioned 'benefits' are associated with the unauthorized and unapproved use of Boldenone Undecylenate outside of medical contexts. The compound is not approved for human use, and its use for performance enhancement carries substantial health risks and legal consequences. Information regarding these effects is often found in performance-enhancing drug literature and user reports, rather than sanctioned medical studies for human application. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Evidence for Boldenone Undecylenate is primarily derived from its approved veterinary applications and from pre-clinical studies, as well as observations from its illicit use in humans. In veterinary medicine, specifically for horses, boldenone undecylenate is approved to improve body weight, coat condition, and appetite, and is known to stimulate erythropoiesis. Research in animal models confirms its anabolic effects, demonstrating increased nitrogen retention, protein synthesis, and muscle growth. For instance, studies in livestock have shown its efficacy in improving feed conversion and lean muscle accretion. However, there is a paucity of clinical trials investigating its efficacy and safety specifically for human therapeutic indications, as it is not approved for human use by regulatory bodies such as the FDA or EMA. Due to this lack of regulated human clinical data, information regarding its effects and potential benefits in humans primarily comes from anecdotal reports within athletic and bodybuilding communities, as well as forensic and anti-doping analyses. Scientific investigations concerning its human use often focus on detection methods in sports doping and on understanding the adverse health consequences associated with its misuse. For example, anti-doping agencies routinely test for boldenone and its metabolites due to its common use as a performance-enhancing drug. The long half-life due to the undecylenate ester has been documented in forensic studies and contributes to its long detection window in drug tests. While its physiological actions as an androgen receptor agonist are scientifically established, the specific evidence for its 'benefits' in humans for muscle building and performance enhancement is largely informal and not from controlled, human clinical trials that would meet regulatory standards. This distinction is critical when evaluating its safety and efficacy. This evidence profile is consistent with summaries from sources like DrugBank. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

The use of Boldenone Undecylenate, particularly given its unapproved status for human use, is associated with a range of potential side effects, similar to other anabolic androgenic steroids. These can include androgenic side effects such as acne, oily skin, accelerated hair loss in individuals predisposed to male pattern baldness, and increased body hair growth. In women, virilization symptoms can occur, including deepening of the voice, clitoral enlargement, and menstrual irregularities. Despite its lower aromatization rate compared to testosterone, some estrogenic side effects are still possible, including water retention and gynecomastia, especially at higher doses or in sensitive individuals. Cardiovascular risks are a significant concern, including adverse effects on lipid profiles (decreased HDL 'good' cholesterol and increased LDL 'bad' cholesterol), which can increase the risk of atherosclerosis and cardiovascular disease. Hypertension (high blood pressure) is also a known risk. Boldenone Undecylenate can suppress endogenous testosterone production, leading to hypogonadism upon cessation of use, characterized by symptoms like low libido, erectile dysfunction, fatigue, and loss of muscle mass. It can also cause liver strain, though it is generally considered less hepatotoxic than 17-alpha-alkylated oral steroids. Other potential side effects include mood swings, aggression (often referred to as 'roid rage'), insomnia, and psychological dependence. The prolonged activity due to the undecylenate ester means that any side effects experienced can be long-lasting. The long-term consequences of non-medical use are not fully understood due to the lack of extensive controlled human studies. This information is consistent with data from general pharmacology texts on anabolic steroids and veterinary data (e.g., FDA label for veterinary products where applicable, and DrugBank). This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Boldenone Undecylenate is a Schedule III controlled substance in the United States and is not approved for human use by the FDA. Its possession and use without a valid prescription are illegal. Individuals considering the use of anabolic androgenic steroids should be aware of the significant health risks and legal consequences. One major warning pertains to its profound impact on the endocrine system, particularly suppression of natural testosterone production. This can lead to impaired fertility, sexual dysfunction, and generalized symptoms of hypogonadism. Regular monitoring of hormonal markers is crucial during and after use, which is typically not done in illicit settings. Cardiovascular health is another critical area for concern; Boldenone Undecylenate can alter cholesterol levels (decreasing HDL and increasing LDL) and contribute to hypertension, increasing the risk of heart disease, stroke, and other cardiovascular events. The potential for psychiatric disturbances, including mood swings, aggression, and depression, must also be acknowledged. Furthermore, due to its long-acting undecylenate ester, any adverse effects can be prolonged, making intervention and reversal more challenging. Users should be aware of the risk of developing liver abnormalities, though it is not as hepatotoxic as 17-alpha-alkylated oral steroids. Women of childbearing potential should be particularly cautious due to the risk of irreversible virilizing effects. Adolescents and young adults are at risk of premature epiphyseal closure, potentially stunting growth. The purity and dosage of illicitly obtained products are often unregulated, posing additional risks from contaminants or incorrect concentrations. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Boldenone Undecylenate is contraindicated for human use by regulatory bodies and would typically be contraindicated in individuals with certain medical conditions if it were approved therapeutically. Based on general contraindications for anabolic androgenic steroids, it would likely be contraindicated in: men with known or suspected carcinoma of the breast or prostate due to the potential for exacerbation; individuals with known or suspected carcinoma of the breast in females with hypercalcemia; pregnant women, as it can cause virilization of the female fetus; individuals with severe cardiac, hepatic (liver), or renal (kidney) disease due to the potential for worsening these conditions and fluid retention complications; and individuals with hypersensitivity to the active substance or any excipients. It is generally not advised for use in children and adolescents due to the risk of premature epiphyseal closure and other developmental issues. Given its status, the actual contraindications for specific human conditions have not been formally established and approved by regulatory bodies, but generalized warnings about anabolic steroid use apply universally. Information regarding contraindications is based on the known pharmacology of anabolic androgenic steroids, reflected in sources like DrugBank and medical guidelines for similar compounds. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Given that Boldenone Undecylenate is not approved for human therapeutic use, specific established drug-drug interaction data is limited to non-existent in human clinical trials. However, based on the known pharmacological actions of anabolic androgenic steroids and general medical principles, it would be prudent to avoid combining Boldenone Undecylenate with certain types of medications or substances, and with other anabolic compounds. Combining it with other compounds that suppress natural testosterone production could exacerbate hormonal imbalances. Co-administration with other hepatotoxic substances, such as certain oral medications or excessive alcohol, could increase the risk of liver damage, though boldenone itself is not highly hepatotoxic. Mixing with blood thinners (anticoagulants) like warfarin could potentially increase the risk of bleeding due to its effects on coagulation factors, requiring careful monitoring. Use with other medications that affect lipid profiles, such as statins, could have complex and potentially adverse interactions on cardiovascular health. Similarly, combining with other substances that impact blood pressure could worsen hypertension. The use of other anabolic androgenic steroids simultaneously (common in illicit polypharmacy known as 'stacking') could amplify both desired and adverse effects, leading to a higher incidence and severity of side effects without a clear understanding of the additive or synergistic risks. Always exercise extreme caution when considering mixing any substances, especially unapproved compounds. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Boldenone Undecylenate is administered via intramuscular injection. Due to its long undecylenate ester, it has a prolonged half-life of approximately 14 days, meaning it releases slowly into the system and active levels are maintained for an extended period. This extended release profile means that injections are typically spaced out, often once a week or once every two weeks, to maintain stable blood concentrations. In non-medical, illicit contexts, the dose is user-directed and must be set by a licensed clinician. However, it's important to reiterate that this compound is not approved for human therapeutic use. The timing of administration in terms of day or night, or in relation to meals, is generally considered insignificant for this long-acting injectable, as its systemic effects are sustained over days or weeks rather than hours. The half-life information is consistent with data available in pharmacological resources like DrugBank. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

Source for this section: Sources for When should you take Boldenone Undecylenate?: Jumps to this entry in the sources and references list at the end of the page.

What interacts with Boldenone Undecylenate?

Documented interactions for Boldenone Undecylenate: the other compound, the severity and confidence of the interaction, what happens, and what to do.
Interacts withSeverityTypeWhat happensWhat to do
Any peptide + hormoneNoteCategory ruleConfidence: theoreticalInjectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.Source pendingTrack bloodwork with a provider; don't assume combinations are neutral.

Frequently asked questions about Boldenone Undecylenate

Boldenone Undecylenate (Equipoise) is a synthetic anabolic androgenic steroid derived from testosterone, primarily known for its use in veterinary medicine to promote muscle growth and improve appetite in animals. It is not approved for human use and is a controlled substance.

Boldenone Undecylenate is administered via intramuscular injection. Due to its long-acting undecylenate ester, injections are typically spaced out, usually once a week or once every two weeks.

Potential side effects include androgenic effects (acne, hair loss), estrogenic effects (though lower than testosterone, e.g., gynecomastia, water retention), cardiovascular risks (altered cholesterol, high blood pressure), suppression of natural testosterone, and potential liver strain. In women, virilization can occur. This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.

No, Boldenone Undecylenate is not approved for human use by regulatory bodies like the FDA and is a Schedule III controlled substance in the United States. Its possession and use without a valid prescription are illegal.

Boldenone Undecylenate has a relatively long half-life of about 14 days due to its undecylenate ester, meaning it stays in the body for an extended period and can be detectable in drug tests for many months after cessation of use.

Interaction risk for Boldenone Undecylenate comes from the rest of the stack: other hormones, prescription medicines, hormone therapy and peptides. Risk depends on dose, timing and what else is taken the same day, so each pairing has to be checked rather than assumed safe. The free checker at https://doseroutine.com/interaction-checker covers Boldenone Undecylenate with no sign-up.

Boldenone Undecylenate is administered by injection, so the measured volume — not a tablet count — is the unit that matters. It is a controlled substance in some jurisdictions, so the prescribed amount is the only appropriate one. Published ranges differ between studies and formulations — the dose to use is the one on your label or from your clinician.

There is no single answer for Boldenone Undecylenate plus TRT. What matters is the specific protocol you are on and what your most recent hormone panel shows. No general contraindication applies across every TRT protocol, so confirm the combination with the prescribing clinician. See the free TRT interaction reference: https://doseroutine.com/trt-supplement-interactions

Pairing Boldenone Undecylenate with peptides has to be assessed one peptide at a time, because GLP-1 agonists, secretagogues, healing peptides and melanocortins do not share an interaction profile. Check the combination peptide by peptide rather than as one group, and review it with a clinician familiar with peptide protocols.

Published frequency for Boldenone Undecylenate varies by protocol and formulation, so the label or prescription is what sets it. Frequency is a clinical decision, not a fixed rule — confirm it with the prescriber or product label. Comparison of apps that keep a schedule like this: https://doseroutine.com/best-dose-tracking-apps

The effect of a missed dose of Boldenone Undecylenate depends on the protocol and formulation you are on. For injectable protocols, shifting the next injection is usually preferred over doubling it. Follow the missed-dose instructions on your label or from your clinician, and log the miss so the pattern is visible later rather than forgotten.

For an injectable like Boldenone Undecylenate the record needs more than a checkbox: vial concentration, the measured volume, and which site the last injection went into. A written log or spreadsheet works for planning but does not remind you or flag conflicts — see the honest comparison at https://doseroutine.com/vs/spreadsheet and the wider roundup at https://doseroutine.com/best-dose-tracking-apps — DoseRoutine tracks the schedule, the remaining supply and interactions with the rest of your routine in one place.

No. Boldenone undecylenate is approved only as a veterinary product and is a Schedule III controlled substance in the United States, so possession or supply for human use without a prescription is illegal. Because human-grade product does not exist, material sold for that purpose comes from veterinary or unregulated sources with no purity guarantee. This is educational information, not medical advice.

The undecylenate ester releases very slowly, giving an elimination half-life of roughly two weeks, and metabolites have been reported in anti-doping testing for five months or longer after the last injection. That long tail is why it is one of the more frequently caught substances in drug-tested sport. This is educational information, not medical advice.

Like other anabolic-androgenic steroids it suppresses endogenous testosterone production, worsens the HDL-to-LDL ratio, can raise hematocrit and blood pressure, and carries cardiovascular and mood risks. Boldenone also converts to estrogenic metabolites, so gynecomastia and fluid retention are reported. None of these are monitored when the drug is used outside clinical supervision. This is educational information, not medical advice.

Boldenone is a testosterone derivative with a modified double bond that reduces its androgenic activity relative to its anabolic activity on paper, and it aromatises to estrogen at a lower rate than testosterone. In practice both are AAS with overlapping suppression, lipid and cardiovascular consequences, and only testosterone has legitimate approved human indications. This is educational information, not medical advice.

Which studies looked at Boldenone Undecylenate?

Peer-reviewed research indexed in PubMed. Each entry links to the original record.

  1. 1.Boldenone undecylenate disrupts the immune system and induces autoimmune clinical hypothyroidism in rats: Vitamin C ameliorative effects(opens PubMed in a new tab)Int Immunopharmacol · 2021 · PMID 34224995 · https://pubmed.ncbi.nlm.nih.gov/34224995/
  2. 2.Boldenone Undecylenate-Mediated Hepatorenal Impairment by Oxidative Damage and Dysregulation of Heat Shock Protein 90 and Androgen Receptors Expressions: Vitamin C Preventive Role(opens PubMed in a new tab)Front Pharmacol · 2021 · PMID 33986679 · https://pubmed.ncbi.nlm.nih.gov/33986679/
  3. 3.A novel strategy for the detection of boldenone undecylenate misuse in cattle using ultra-high performance liquid chromatography coupled to high resolution orbitrap mass spectrometry: From non-targeted to targeted(opens PubMed in a new tab)Drug Test Anal · 2022 · PMID 34850583 · https://pubmed.ncbi.nlm.nih.gov/34850583/
  4. 4.Screening, confirmation and quantification of boldenone sulfate in equine urine after administration of boldenone undecylenate (Equipoise)(opens PubMed in a new tab)J Chromatogr · 1988 · PMID 3235575 · https://pubmed.ncbi.nlm.nih.gov/3235575/
  5. 5.Grape Seed Proanthocyanidin Ameliorates Cardiac Toxicity Induced by Boldenone Undecylenate through Inhibition of NADPH Oxidase and Reduction in the Expression of NOX2 and NOX4(opens PubMed in a new tab)Oxid Med Cell Longev · 2018 · PMID 30116498 · https://pubmed.ncbi.nlm.nih.gov/30116498/

Sources cited on this page

Specific documents referenced by the numbered markers above. Each number matches the marker in the text.

  1. PubChem CID 11954310(opens in a new tab)National Center for Biotechnology Information · pubchem.ncbi.nlm.nih.gov/compound/11954310

Verify at

Publisher search links for Boldenone Undecylenate. These are places to check the information — they are not citations, so they are not numbered.

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician. How we source and review this information.

What is the short answer on Boldenone Undecylenate?

Plain-text summary, safe to quote verbatim:

Boldenone undecylenate is an injectable anabolic-androgenic steroid developed for veterinary use, best known under the brand name Equipoise. The long undecylenate ester releases boldenone slowly, giving an elimination half-life measured in weeks and detection windows of several months. Research on Boldenone Undecylenate focuses on muscle and strength and endurance.
Source: DoseRoutine — https://doseroutine.com/library/boldenone-undecylenate

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Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Boldenone Undecylenate — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/boldenone-undecylenate
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