Can you take these together? 235 answered pairs
Every page below answers one question in plain English: what happens when two specific things in a routine are taken together, why it happens, and what to do about the timing. Pairs are drawn from the same rule set that powers the DoseRoutine interaction checker, which reviews your whole stack at once instead of one pair at a time.
Showing 235 of 235 pairs
- 5-HTP and DuloxetineAvoid
- 5-HTP and EscitalopramAvoid
- 5-HTP and FluoxetineAvoid
- 5-HTP and SertralineAvoid
- 5-HTP and VenlafaxineAvoid
- Alpha-Lipoic Acid and MetforminNote
- Alpha-GPC and AniracetamComplementary
- Alpha-GPC and PiracetamComplementary
- Amantadine and AmlodipineCaution
- Amantadine and BupropionCaution
- Amantadine and CaffeineCaution
- Amantadine and LisinoprilCaution
- Amantadine and MetoprololCaution
- Amantadine and SertralineCaution
- Amantadine and SildenafilCaution
- Amantadine and St John's WortCaution
- Amantadine and TadalafilCaution
- Amantadine and VardenafilCaution
- Amlodipine and SildenafilCaution
- Amlodipine and TadalafilCaution
- Amlodipine and VardenafilCaution
- Amphetamine Salts and CaffeineCaution
- Amphetamine Salts and PhenelzineAvoid
- Amphetamine Salts and SelegilineAvoid
- Amphetamine Salts and TranylcypromineAvoid
- Amphetamine Salts and Yohimbine HClAvoid
- Anastrozole (Arimidex) and Testosterone CypionateComplementary
- Anastrozole (Arimidex) and Testosterone (TRT)Complementary
- Apixaban and BromelainCaution
- Apixaban and CurcuminCaution
- Apixaban and Fish Oil (High EPA)Caution
- Apixaban and Krill OilCaution
- Apixaban and Omega-3 (Fish Oil)Caution
- Apixaban and SerrapeptaseCaution
- Apixaban and Vitamin ECaution
- Apixaban and Vitamin K1Caution
- Apixaban and Vitamin K2Caution
- Ashwagandha and LevothyroxineNote
- Ashwagandha and ZolpidemNote
- Atorvastatin and BerberineCaution
- Atorvastatin and CoQ10 (Ubiquinol)Complementary
- Atorvastatin and RapamycinCaution
- Atorvastatin and UbiquinolComplementary
- Berberine and LovastatinCaution
- Berberine and MetforminCaution
- Berberine and PravastatinCaution
- Berberine and RosuvastatinCaution
- Berberine and SimvastatinCaution
- Bromelain and ClopidogrelCaution
- Bromelain and DabigatranCaution
- Bromelain and RivaroxabanCaution
- Bromelain and WarfarinCaution
- Caffeine and Creatine MonohydrateNote
- Caffeine and Iron (ferrous bisglycinate)Caution
- Caffeine and L-TheanineComplementary
- Caffeine and LisdexamfetamineCaution
- Caffeine and MethylphenidateCaution
- Calcium and Iron (ferrous bisglycinate)Caution
- Calcium and LevothyroxineCaution
- Calcium and LiothyronineCaution
- Calcium and Magnesium GlycinateNote
- Calcium and ZincCaution
- CDP-Choline and OxiracetamComplementary
- Citalopram and PhenelzineAvoid
- Citalopram and RasagilineAvoid
- Citalopram and SelegilineAvoid
- Citalopram and TranylcypromineAvoid
- CJC-1295 and IGF-1 LR3Caution
- CJC-1295 and IpamorelinNote
- CJC-1295 and SermorelinCaution
- Clopidogrel and CurcuminCaution
- Clopidogrel and Fish Oil (High EPA)Caution
- Clopidogrel and Krill OilCaution
- Clopidogrel and Omega-3 (Fish Oil)Caution
- Clopidogrel and SerrapeptaseCaution
- Clopidogrel and Vitamin ECaution
- Clopidogrel and Vitamin K1Caution
- Clopidogrel and Vitamin K2Caution
- Copper and ZincNote
- Copper and Zinc PicolinateNote
- CoQ10 (Ubiquinol) and LovastatinComplementary
- CoQ10 (Ubiquinol) and PQQComplementary
- CoQ10 (Ubiquinol) and PravastatinComplementary
- CoQ10 (Ubiquinol) and RosuvastatinComplementary
- CoQ10 (Ubiquinol) and SimvastatinComplementary
- CoQ10 (Ubiquinol) and WarfarinCaution
- Curcumin and DabigatranCaution
- Curcumin and RivaroxabanCaution
- Curcumin and WarfarinCaution
- Dabigatran and Fish Oil (High EPA)Caution
- Dabigatran and Krill OilCaution
- Dabigatran and Omega-3 (Fish Oil)Caution
- Dabigatran and SerrapeptaseCaution
- Dabigatran and Vitamin ECaution
- Dabigatran and Vitamin K1Caution
- Dabigatran and Vitamin K2Caution
- Dexmethylphenidate and PhenelzineAvoid
- Dexmethylphenidate and SelegilineAvoid
- Dexmethylphenidate and TranylcypromineAvoid
- Diphenhydramine and MelatoninNote
- Dulaglutide and Insulin (Long-Acting)Caution
- Dulaglutide and Insulin (Rapid)Caution
- Duloxetine and L-TryptophanCaution
- Duloxetine and PhenelzineAvoid
- Duloxetine and RasagilineAvoid
- Duloxetine and SelegilineAvoid
- Duloxetine and St John's WortAvoid
- Duloxetine and TranylcypromineAvoid
- Dutasteride and Testosterone CypionateCaution
- Enalapril and SildenafilCaution
- Enalapril and TadalafilCaution
- Enalapril and VardenafilCaution
- Escitalopram and L-TryptophanCaution
- Escitalopram and PhenelzineAvoid
- Escitalopram and RasagilineAvoid
- Escitalopram and SelegilineAvoid
- Escitalopram and St John's WortAvoid
- Escitalopram and TranylcypromineAvoid
- Esomeprazole and LevothyroxineCaution
- Eszopiclone and MelatoninNote
- Exenatide and Insulin (Long-Acting)Caution
- Exenatide and Insulin (Rapid)Caution
- Finasteride 1mg and Testosterone CypionateCaution
- Finasteride and Testosterone CypionateCaution
- Fish Oil (High EPA) and RivaroxabanCaution
- Fish Oil (High EPA) and WarfarinCaution
- Fluoxetine and L-TryptophanCaution
- Fluoxetine and PhenelzineAvoid
- Fluoxetine and RasagilineAvoid
- Fluoxetine and SelegilineAvoid
- Fluoxetine and St John's WortAvoid
- Fluoxetine and TranylcypromineAvoid
- Glutathione and NAC (N-Acetyl Cysteine)Note
- HCG and Testosterone CypionateComplementary
- Hordenine and PhenelzineAvoid
- Hordenine and SelegilineAvoid
- Hordenine and TranylcypromineAvoid
- IGF-1 LR3 and SermorelinCaution
- IGF-1 LR3 and TesamorelinCaution
- Insulin (Long-Acting) and LiraglutideCaution
- Insulin (Long-Acting) and RetatrutideCaution
- Insulin (Long-Acting) and SemaglutideCaution
- Insulin (Long-Acting) and SurvodutideCaution
- Insulin (Long-Acting) and TirzepatideCaution
- Insulin (Rapid) and LiraglutideCaution
- Insulin (Rapid) and RetatrutideCaution
- Insulin (Rapid) and SemaglutideCaution
- Insulin (Rapid) and SurvodutideCaution
- Insulin (Rapid) and TirzepatideCaution
- Iron (ferrous bisglycinate) and LevothyroxineCaution
- Iron (ferrous bisglycinate) and LiothyronineCaution
- Iron (ferrous bisglycinate) and Vitamin CComplementary
- Krill Oil and RivaroxabanCaution
- Krill Oil and WarfarinCaution
- L-Tryptophan and SertralineCaution
- L-Tryptophan and VenlafaxineCaution
- Lansoprazole and LevothyroxineCaution
- Levothyroxine and Magnesium CitrateCaution
- Levothyroxine and Magnesium GlycinateCaution
- Levothyroxine and Magnesium OxideCaution
- Levothyroxine and OmeprazoleCaution
- Levothyroxine and Omeprazole (Prilosec)Caution
- Levothyroxine and PantoprazoleCaution
- Levothyroxine and ZincCaution
- Levothyroxine and Zinc BisglycinateCaution
- Levothyroxine and Zinc PicolinateCaution
- Liothyronine and Magnesium GlycinateCaution
- Lisdexamfetamine and PhenelzineAvoid
- Lisdexamfetamine and SelegilineAvoid
- Lisdexamfetamine and TranylcypromineAvoid
- Lisdexamfetamine and Yohimbine HClAvoid
- Lisinopril and PotassiumCaution
- Lisinopril and SildenafilCaution
- Lisinopril and TadalafilCaution
- Lisinopril and VardenafilCaution
- Losartan and SildenafilCaution
- Losartan and TadalafilCaution
- Losartan and VardenafilCaution
- Lovastatin and UbiquinolComplementary
- Magnesium Glycinate and Vitamin D3Complementary
- Melatonin and MirtazapineNote
- Melatonin and SuvorexantNote
- Melatonin and TrazodoneNote
- Melatonin and ZolpidemNote
- Metformin and MK-677Note
- Metformin and Vitamin B12Note
- Metformin ER and Vitamin B12Note
- Metformin Immediate Release and Vitamin B12Note
- Methylphenidate and PhenelzineAvoid
- Methylphenidate and SelegilineAvoid
- Methylphenidate and TranylcypromineAvoid
- Methylphenidate and Yohimbine HClAvoid
- MK-677 and SemaglutideNote
- NMN and Nicotinamide Riboside (NR)Note
- Omega-3 (Fish Oil) and RivaroxabanCaution
- Omega-3 (Fish Oil) and WarfarinCaution
- Paroxetine and PhenelzineAvoid
- Paroxetine and RasagilineAvoid
- Paroxetine and SelegilineAvoid
- Paroxetine and TranylcypromineAvoid
- Phenelzine and SertralineAvoid
- Phenelzine and SynephrineAvoid
- Phenelzine and VenlafaxineAvoid
- Phenelzine and Yohimbine HClAvoid
- Pravastatin and UbiquinolComplementary
- Ramipril and SildenafilCaution
- Ramipril and TadalafilCaution
- Ramipril and VardenafilCaution
- Rasagiline and SertralineAvoid
- Rasagiline and VenlafaxineAvoid
- Rivaroxaban and SerrapeptaseCaution
- Rivaroxaban and Vitamin ECaution
- Rivaroxaban and Vitamin K1Caution
- Rivaroxaban and Vitamin K2Caution
- Rosuvastatin and UbiquinolComplementary
- Selegiline and SertralineAvoid
- Selegiline and SynephrineAvoid
- Selegiline and VenlafaxineAvoid
- Selegiline and Yohimbine HClAvoid
- Serrapeptase and WarfarinCaution
- Sertraline and St John's WortAvoid
- Sertraline and TranylcypromineAvoid
- Sildenafil and ValsartanCaution
- Simvastatin and UbiquinolComplementary
- St John's Wort and VenlafaxineAvoid
- Synephrine and TranylcypromineAvoid
- Tadalafil and ValsartanCaution
- Tranylcypromine and VenlafaxineAvoid
- Tranylcypromine and Yohimbine HClAvoid
- Valsartan and VardenafilCaution
- Vitamin D3 and Vitamin K2Complementary
- Vitamin D3 and Vitamin K2 MK-7Complementary
- Vitamin E and WarfarinCaution
- Vitamin K1 and WarfarinCaution
- Vitamin K2 and WarfarinAvoid
Asked as a question
Every pair above also has a short answer-first page in the form /is/<a>-safe-with-<b> — for example Is 5-HTP safe with Duloxetine?
Buying and handling matter more than most pairings: how to protect yourself from counterfeits and handling mistakes.
Educational information only, not medical advice. Talk to your prescriber before starting, stopping or combining anything.
About these interaction pages
What is an interaction pair page?
Each pair page answers one question — 'can I take A with B?' — with a direct verdict, the mechanism behind the interaction, the recommended spacing where spacing helps, and the sources the conclusion came from. Every named pair in the DoseRoutine rule set has one.
My combination isn't listed. Is it safe?
Not necessarily. A missing pair page means no named rule exists yet, not that the combination is cleared. Run both items through the interaction checker — it applies category-level rules (for example, all nephrotoxic items, or all CYP3A4 inducers) that catch combinations without a dedicated page.
How are severities assigned?
Each rule is graded Avoid, Caution, or Note based on the strength and consequence of the documented interaction, and each grade carries the citation it was drawn from. Grades reflect the published literature and label documentation, not an opinion about whether you should take something.
Do you cover supplements against prescriptions?
Yes. Pair coverage spans supplements, vitamins and minerals, peptides, hormones and TRT, GLP-1 medications and common daily prescriptions, in any combination.