Can you take Metformin and Vitamin B12 together?
Yes — but there is one thing worth knowing.
Metformin and Vitamin B12 can be taken together — there is one detail worth knowing first.
Why these two interact
Long-term metformin use is associated with reduced B12 absorption and lower serum B12.
What to do about it
Monitor B12 annually; supplement 500–1000 mcg/day if low.
Timing
No fixed separation window applies here. Keep the timing consistent day to day so any effect is easy to spot.
The two items in this pair
Check your whole routine, not just this pair
One pair rarely tells the whole story. DoseRoutine checks every combination in your stack at once — supplements, TRT, peptides, GLP-1s and prescriptions — and schedules the doses so timing conflicts like this one are handled automatically.
Frequently asked
Related combinations
Educational information only, not medical advice. DoseRoutine does not diagnose or treat. Talk to your prescriber before starting, stopping or combining anything — especially if you take prescription medication or are pregnant or breastfeeding.