hormoneInjectableControlledSchedule III (US)Prescription only (US)
Nandrolone DecanoateBenefits, Dosage & Interactions
Also known as: Deca-Durabolin
Nandrolone decanoate is a synthetic anabolic androgenic steroid (AAS) derived from testosterone. It is known by its common brand name, Deca-Durabolin. Research on Nandrolone Decanoate focuses on bone and joint health and muscle and strength. Nandrolone Decanoate is administered by injection rather than orally.
How much Nandrolone Decanoate do people take?
100 mg weekly in the hemodialysis trial; 100-150 mg every 2 weeks in the HIV weight-loss trial. Route reported: Intramuscular. Frequency reported: Weekly to every 2 weeks in those trials. These are amounts documented in the cited studies and labels for Nandrolone Decanoate — they are reported for reference, not a recommendation. Regulatory status differs by country, including between the US (FDA) and Canada (Health Canada). Confirm any amount with a licensed clinician before you take it.
See the full reported protocol and its sourcesResearched by DoseRoutine Research TeamReviewed for accuracy by Nicholas Alexander, RSE, SO, PMPLast updated Educational reference only — not medical advice. Always confirm dosing and safety decisions with a licensed clinician.
Evidence: Strong — 2 human randomized trials and regulatory approval on file.
Evidence strengthStrong · 4/4
PreclinicalStrong human evidence
2 human randomized trials and regulatory approval on file.
Plasma half-life
~144 h
Default unit
mg
What published protocols report
Ranges documented in the literature, shown for reference. DoseRoutine does not recommend an amount — your prescriber or the product label sets the dose.
Reported for Nandrolone Decanoate in the cited sources. Published ranges are not dosing advice.
Mixing Nandrolone Decanoate: bacteriostatic water and syringe units
The vial arrives as dry powder. How much water you add sets the strength, and the strength sets the mark you draw to on the syringe. The table assumes a 5 mg vial and a 250 mcg example draw on a U-100 insulin syringe, where 100 units is one millilitre. If your vial is a different size, scale it — the arithmetic is the same.
| Bacteriostatic water added | Resulting strength | 250 mcg draws to |
|---|---|---|
| 1 mL | 5 mg/mL | 5 units |
| 2 mL | 2.5 mg/mL | 10 units |
| 3 mL | 1.67 mg/mL | 15 units |
Units, not millilitres. Insulin syringes are marked in units, and mixing up mcg and mg on a peptide label is the single most common error people report. Check the label twice. Run your own vial through the calculator.
Storage and stability
- Before mixing
- Sealed and still as a dry powder, Nandrolone Decanoate vials are normally kept in the fridge at 2–8 °C, out of light. Short spells at room temperature during shipping are the norm for lyophilized peptides and are not, on their own, a sign the vial is spoiled.
- After mixing
- Once bacteriostatic water goes in, the vial belongs in the fridge and is generally treated as good for about 28 days — that is how long the benzyl alcohol in bacteriostatic water is relied on to hold back bacterial growth. Plain sterile water has no preservative, so a vial mixed with it is a single-session vial. Never freeze a reconstituted vial.
- When to throw it out
- A properly mixed vial is clear. Cloudiness, floating strands, a color change or powder that will not go into solution after gentle swirling all mean the vial should be discarded rather than used. Shaking a peptide vial hard is the usual cause — swirl it, or run the water down the inside wall of the vial instead of onto the powder.
Handling and shelf-life figures describe general practice for lyophilized peptides. They are not a dose and not medical advice — your prescriber or the product label sets the amount.
Nandrolone Decanoate compared with similar compounds
| Attribute | Testosterone enanthate | Nandrolone decanoate | Oxandrolone |
|---|---|---|---|
| Class | Injectable androgen ester | 19-nortestosterone ester | Oral 17-alpha-alkylated androgen |
| Route | Intramuscular | Intramuscular | Oral |
| Half-life | 4-5 days | 6-12 days | ~9 hours |
| Evidence grade | Strong | Moderate | Moderate |
| Oral stability | Not orally used | Not orally used | Orally active |
| Typical published cycle | Ongoing while prescribed | 12 weeks to 6 months in the wasting trials | Weeks to months in the burn trials |
| Main studied use | Male hypogonadism | Wasting in dialysis and HIV | Lean mass after severe burns |
References & evidence
Documents the Nandrolone Decanoate entry is written from. Each number matches an inline marker above.
- [1]Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: a randomized, controlled trialJohansen KL, Painter PL, Sakkas GK, et al. · Journal of the American Society of Nephrology · 2006 · Peer-reviewed · PMID 16825332
- [2]Effect of nandrolone decanoate therapy on weight and lean body mass in HIV-infected women with weight loss: a randomized, double-blind, placebo-controlled, multicenter trialMulligan K, Zackin R, Clark RA, et al. · Archives of Internal Medicine · 2005 · Peer-reviewed · PMID 15767536
References & Evidence
Sources on this page that document Nandrolone Decanoate dosing, timing and safety.
- [1]National Center for Biotechnology Information View source
Educational information only — not medical advice. Dose ranges vary by person, indication and prescriber.
What is Nandrolone Decanoate studied for?
What is Nandrolone Decanoate?Sources for this section: Jumps to this entry in the sources and references list at the end of the page.
Nandrolone decanoate is a synthetic anabolic androgenic steroid (AAS) derived from testosterone. It is known by its common brand name, Deca-Durabolin. As an AAS, it shares structural similarities with testosterone but has a modified chemical structure that gives it a higher anabolic (tissue-building) to androgenic (masculinizing) ratio compared to testosterone. This characteristic is often cited as a reason for its therapeutic use where anabolic effects are desired with fewer androgenic side effects.
Historically, nandrolone decanoate has been used in various medical contexts, including in the treatment of anemia associated with renal insufficiency, osteoporosis in postmenopausal women, and catabolic states such following severe burns or extensive surgery. Its ability to promote lean body mass and bone density has been of particular interest in these therapeutic applications. However, its use has become more restricted due to changing medical guidelines and the availability of alternative treatments (DrugBank, FDA label).
Pharmacologically, nandrolone decanoate is an ester of nandrolone. The decanoate ester prolongs the release of nandrolone from the injection site, resulting in a sustained therapeutic effect over an extended period. This long half-life means that injections are typically spaced out, often weekly or bi-weekly, depending on the therapeutic regimen. Due to its classification as a controlled substance in many countries, its medical use is strictly regulated and requires a prescription.
What does the research say about Nandrolone Decanoate?
Tap a section to expand.
Nandrolone decanoate functions primarily by binding to androgen receptors within various tissues, including skeletal muscle, bone, and certain hematopoietic precursor cells. Upon intramuscular injection, the decanoate ester is slowly hydrolyzed, releasing nandrolone into the systemic circulation. Nandrolone then acts as an agonist at the androgen receptor.
Key mechanisms of action include:
* **Protein Synthesis Enhancement:** By binding to androgen receptors in muscle cells, nandrolone promotes gene transcription linked to protein synthesis. This leads to an increase in muscle protein accumulation and overall lean body mass (Examine.com).
* **Nitrogen Retention:** Nandrolone helps improve nitrogen balance within the body. A positive nitrogen balance is crucial for muscle growth and repair, as nitrogen is a fundamental component of amino acids, the building blocks of proteins (DrugBank).
* **Increased Red Blood Cell Production:** It stimulates erythropoiesis (the production of red blood cells) in the bone marrow. This effect contributes to its historical use in treating anemia, particularly in patients with chronic kidney disease (FDA label).
* **Bone Mineral Density Improvement:** Nandrolone can promote calcium retention and protein anabolism in the bone matrix, which contributes to increased bone density and strength. This mechanism formed the basis for its use in osteoporosis (DrugBank).
* **Reduced Glucocorticoid Receptor Binding:** Some research suggests that nandrolone may have a degree of antagonistic activity or interference with glucocorticoid receptor binding, potentially mitigating the catabolic effects of stress hormones like cortisol (PubChem).
Unlike testosterone, nandrolone has a reduced tendency to convert into dihydrotestosterone (DHT) due to its structural modifications. Instead, it is primarily metabolized to dihydronandrolone. It also has a relatively low rate of aromatization (conversion to estrogen) compared to testosterone, though some estrogenic activity can still occur (DrugBank).
Source for this section: Sources for How does Nandrolone Decanoate work?: Jumps to this entry in the sources and references list at the end of the page.
Nandrolone decanoate has been associated with several potential therapeutic benefits, primarily due to its anabolic properties.
* **Muscle Mass Increase:** Its primary benefit in clinical settings is the promotion of lean body mass. This has been medically useful in patients experiencing severe muscle wasting due to chronic illnesses, extensive surgeries, or burns. The anabolic effects help in tissue repair and rebuilding (PubChem, DrugBank).
* **Bone Density Improvement:** Nandrolone has demonstrated efficacy in increasing bone mineral density. This was a key benefit for its use in treating osteoporosis, especially in postmenopausal women, by enhancing calcium retention and bone anabolism (FDA label).
* **Treatment of Anemia:** Due to its ability to stimulate erythropoiesis, nandrolone decanoate has been employed in the management of anemia, particularly in patients with chronic renal insufficiency where erythropoietin production is often impaired (NIH ODS).
* **Recovery Enhancement:** In certain catabolic states, nandrolone can aid in overall recovery by improving protein synthesis and accelerating tissue repair, which can contribute to faster recuperation following injury or illness (Mayo Clinic).
* **Appetite Stimulation:** Some patients receiving nandrolone decanoate have reported an increase in appetite, which can be beneficial in conditions characterized by cachexia or unintentional weight loss. However, this is generally a secondary effect of its broader anabolic actions (MedlinePlus).
It is important to note that the medical indications for nandrolone decanoate have evolved, and its use is now more specialized, with a focus on specific patient populations where the benefits outweigh the potential risks and alternative therapies may not be suitable.
Evidence regarding nandrolone decanoate's efficacy stems from a range of clinical studies, primarily conducted in the mid-to-late 20th century before the widespread availability of newer therapeutic agents.
For **anemia of chronic renal failure**, studies demonstrated that nandrolone decanoate could increase hemoglobin levels and red blood cell counts by stimulating erythropoiesis. A systematic review published in the Cochrane Library, examining various anabolic steroids for anemia, noted nandrolone's effectiveness in improving hematological parameters, though often with significant side effects (Cochrane).
In the context of **osteoporosis**, clinical trials investigated nandrolone decanoate's impact on bone mineral density. Research summarized by sources like NIH ODS indicated that regular administration could lead to significant increases in bone density, especially in the lumbar spine, and could help reduce the incidence of vertebral fractures in postmenopausal women with osteoporosis. However, the exact mechanisms and long-term safety profile, especially concerning cardiovascular and hepatic effects, led to a re-evaluation of its risk-benefit profile over time.
Regarding **muscle wasting and catabolic states**, evidence from clinical observations and smaller trials supported its utility in promoting positive nitrogen balance and lean body mass gain in patients with severe burns, chronic debilitating illnesses, or after major surgery. These studies, often cited within sources like medical textbooks and pharmaceutical monographs (e.g., DrugBank), showed improvements in overall physical condition and recovery rates. However, the precise extent of its benefit relative to rehabilitation efforts and nutritional support is complex to isolate.
The widespread non-medical use of nandrolone decanoate has also led to extensive research into its effects on athletic performance and body composition, but this research often falls outside the scope of regulated medical indications (Examine.com). Overall, while historical evidence supports its therapeutic properties, its use is now reserved for specific, carefully selected cases under strict medical supervision due to safety concerns and better-tolerated alternatives.
Nandrolone decanoate, like other anabolic androgenic steroids, can cause a range of side effects affecting multiple body systems. The severity and incidence of these effects can depend on the dosage, duration of use, individual susceptibility, and other concurrent medications or health conditions.
Commonly reported side effects include (FDA label, MedlinePlus):
* **Androgenic Effects:** Despite its lower androgenic rating compared to testosterone, virilization can occur, especially in women and prepubertal males. This can manifest as hirsutism (excess body hair), voice deepening, clitoral enlargement, and male-pattern baldness. In males, it can cause acne, increased libido, and priapism.
* **Cardiovascular Effects:** Sustained use can lead to adverse changes in lipid profiles, typically characterized by decreased high-density lipoprotein (HDL) cholesterol and increased low-density lipoprotein (LDL) cholesterol, which can increase the risk of cardiovascular disease. It may also contribute to hypertension and other cardiac issues.
* **Hepatic Effects:** While less hepatotoxic than 17-alpha alkylated oral steroids, nandrolone decanoate can still cause liver dysfunction. This may include elevated liver enzymes, jaundice, and, in rare cases, peliosis hepatis or hepatic tumors.
* **Endocrine Effects:** In males, it can suppress endogenous testosterone production, leading to testicular atrophy, impaired spermatogenesis, and erectile dysfunction. It can also cause gynecomastia (breast enlargement) due to its potential for aromatization to estrogen. In women, menstrual irregularities can occur.
* **Psychiatric Effects:** Mood disturbances, including increased aggression, irritability, depression, and anxiety, have been reported by individuals using anabolic steroids.
* **Fluid and Electrolyte Disturbances:** Sodium, chloride, potassium, calcium, and phosphate retention can occur, leading to edema.
* **Musculoskeletal Effects:** In adolescents, premature epiphyseal closure can result in stunted growth.
* **Injection Site Reactions:** Pain, swelling, or irritation at the injection site are common.
This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.
Given its potent pharmacological activity, several significant warnings are associated with the use of nandrolone decanoate.
* **Liver Toxicity:** While less severe than oral anabolic steroids, nandrolone decanoate can still affect liver function. Patients should be monitored for signs of hepatic impairment, and it should be used with extreme caution in individuals with pre-existing liver disease (DrugBank).
* **Cardiovascular Risk:** Anabolic steroids, including nandrolone decanoate, can profoundly impact lipid profiles, increasing LDL and decreasing HDL cholesterol. This can elevate the risk of atherosclerosis, myocardial infarction, and stroke. Cardiovascular health should be closely monitored during therapy (FDA label).
* **Endocrine Disruption:** In males, exogenous androgen administration suppresses endogenous testosterone production, potentially leading to hypogonadism (testicular atrophy, infertility) upon cessation. In females, virilization is a significant concern, which may be irreversible even after discontinuation (Mayo Clinic).
* **Fluid Retention:** Nandrolone decanoate can cause sodium and water retention, leading to edema and potentially exacerbating conditions like congestive heart failure, renal impairment, and hypertension (MedlinePlus).
* **Psychiatric Effects:** Users may experience mood swings, aggression, irritability, and depressive symptoms. Individuals with a history of psychiatric disorders should use this compound with extreme caution and under close supervision.
* **Potential for Abuse:** Due to its anabolic properties, nandrolone decanoate is subject to abuse by athletes and bodybuilders for non-medical performance enhancement, often at supraphysiological doses. Such misuse carries significant health risks beyond therapeutic use.
* **Cancer Risk:** There is a known association between long-term high-dose anabolic steroid use and an increased risk of certain cancers, particularly hepatocellular carcinoma and prostatic carcinoma (PubChem).
* **Diabetic Patients:** Anabolic steroids can alter glucose tolerance and insulin sensitivity. Diabetic patients should be closely monitored.
This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.
Nandrolone decanoate is contraindicated in several medical conditions due to the potential for severe adverse effects.
* **Known Hypersensitivity:** Patients with a documented allergy or hypersensitivity to nandrolone decanoate or any of its excipients should not use this compound.
* **Male Patients with Carcinoma of the Breast or Prostate:** Anabolic steroids can stimulate the growth of certain hormone-sensitive cancers. Therefore, it is strictly contraindicated in men with known or suspected breast carcinoma or prostate carcinoma (NIH ODS).
* **Pregnancy and Breastfeeding:** Nandrolone decanoate is classified as a Pregnancy Category X drug. It can cause severe harm to a developing fetus, including virilization of a female fetus. It is also contraindicated during breastfeeding due to the potential for harm to the infant (FDA label).
* **Nephrosis or the Nephrotic Phase of Nephritis:** Due to the potential for fluid retention and electrolyte disturbances, it is contraindicated in patients with severe kidney disease, particularly those in nephrotic syndrome, which is characterized by significant protein loss in the urine and edema.
* **Severe Liver Impairment:** Although less hepatotoxic than some other steroids, severe liver compromise is a contraindication given the metabolic load and potential for exacerbation of liver disease (DrugBank).
* **Hypercalcemia:** In some cases, anabolic steroids can lead to hypercalcemia, particularly in patients who are immobilized. Therefore, it is contraindicated in patients with pre-existing high calcium levels.
* **Cardiac Failure:** Due to the risk of fluid retention and its impact on the cardiovascular system, it is generally contraindicated in individuals with severe cardiac failure.
This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.
Mixing nandrolone decanoate with certain medications or substances can lead to increased risks or altered effects. It is crucial to inform your clinician about all medications, supplements, and illicit substances you are using.
* **Oral Anticoagulants (e.g., Warfarin):** Anabolic steroids can enhance the anticoagulant activity, leading to an increased risk of bleeding. Close monitoring of coagulation parameters (e.g., INR) and anticoagulant dose adjustment are necessary.
* **Corticosteroids:** Concomitant use with corticosteroids can increase the risk of edema and fluid retention, particularly in patients with pre-existing cardiac or renal conditions.
* **Insulin and Oral Hypoglycemic Agents:** Anabolic steroids can alter glucose metabolism and insulin sensitivity, potentially leading to hypoglycemia. Doses of antidiabetic medications may require adjustment.
* **Adrenocorticotropic Hormone (ACTH):** Similar to corticosteroids, concurrent use with ACTH can increase the risk of edema.
* **Immunosuppressants (e.g., Cyclosporine):** There may be potential interactions impacting drug metabolism or increasing toxicity, though specific data for nandrolone decanoate is limited compared to other steroids.
* **Other Hepatotoxic Agents:** Combining nandrolone decanoate with other substances known to be toxic to the liver (e.g., certain medications, excessive alcohol) can increase the risk of liver damage.
* **Tamoxifen and Other Anti-estrogens:** While nandrolone has a low aromatization rate, some may still convert to estrogen. The interaction with anti-estrogen medications should be considered in specific clinical contexts.
* **Diuretics:** The fluid-retaining effects of nandrolone decanoate may counteract the effects of diuretics; adjustments to diuretic therapy might be necessary.
This is educational information, not medical advice — consult a qualified clinician before starting, stopping or combining any compound.
Nandrolone decanoate is an injectable compound. Its typical medical timing is user-directed and must be set by a licensed clinician. Due to its long-acting decanoate ester, it characteristically has a prolonged release profile into the bloodstream. This property allows for infrequent dosing schedules, typically ranging from once a week to once every two to three weeks, depending on the specific medical condition being treated and individual patient response. The goal of such a schedule is to maintain stable therapeutic concentrations of nandrolone over an extended period. The compound can be administered intramuscularly at any time of day, as its long half-life of approximately 360 hours means that the immediate timing of injection relative to food intake or daily activities is not as critical as with short-acting medications (DrugBank, FDA label). Consistency in the injection schedule is generally more important than the exact time of day for each dose to ensure stable blood levels.
Source for this section: Sources for When should you take Nandrolone Decanoate?: Jumps to this entry in the sources and references list at the end of the page.
Put it into practice
Reading about Nandrolone Decanoate is the first step — DoseRoutine helps you act on it. These free tools turn what you just learned into a routine.
What interacts with Nandrolone Decanoate?
| Interacts with | Severity | Type | What happens | What to do |
|---|---|---|---|---|
| Any peptide + hormone | Note | Category ruleConfidence: theoretical | Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.Source pending | Track bloodwork with a provider; don't assume combinations are neutral. |
Frequently asked questions about Nandrolone Decanoate
Nandrolone decanoate has been used in medical settings to treat conditions such as anemia associated with chronic renal failure, osteoporosis in postmenopausal women, and severe catabolic states like those following major surgery or extensive burns, to promote muscle mass and bone density. Its use is now more restricted due to safety concerns and alternative treatments (FDA label).
Nandrolone Decanoate works by binding to androgen receptors in various tissues, stimulating protein synthesis, improving nitrogen balance, increasing red blood cell production, and enhancing bone mineral density. These actions contribute to its anabolic (tissue-building) effects (DrugBank).
Side effects can include virilization (development of male characteristics) in women, suppression of natural testosterone production in men, adverse changes in cholesterol levels, liver dysfunction, fluid retention, and mood changes (MedlinePlus).
Yes, in many countries, including the United States, nandrolone decanoate is classified as a Schedule III controlled substance due to its potential for abuse and dependence (NIH ODS).
While it has been used in women for certain medical conditions (e.g., osteoporosis), its use in women is often limited due to the high risk of virilization, which can be irreversible even after stopping the compound. Any use must be carefully weighed against these risks by a clinician (Mayo Clinic).
Nandrolone Decanoate is a hormone, and interactions are possible with prescriptions, hormones, peptides and other supplements in the same routine. With a reported plasma half-life near 144 hours, separating doses can change the picture as much as removing one. Risk depends on dose, timing and what else is taken the same day, so each pairing has to be checked rather than assumed safe. The free checker at https://doseroutine.com/interaction-checker covers Nandrolone Decanoate with no sign-up.
Nandrolone Decanoate is administered by injection, so the measured volume — not a tablet count — is the unit that matters. The reported plasma half-life is about 144 hours, which is what drives how often it is redosed. It is a controlled substance in some jurisdictions, so the prescribed amount is the only appropriate one. Ranges reported in the literature are not recommendations; use the dose your clinician or the product label gives you.
Combining a hormone like Nandrolone Decanoate with TRT is usually a question of labs rather than a blanket yes or no: the ester, injection interval and any aromatase inhibitor all change the answer. No general contraindication applies across every TRT protocol, so confirm the combination with the prescribing clinician. See the free TRT interaction reference: https://doseroutine.com/trt-supplement-interactions
Each peptide class carries its own profile against Nandrolone Decanoate: a healing peptide raises different questions than a GLP-1 agonist or a growth-hormone secretagogue. Check the combination peptide by peptide rather than as one group, and review it with a clinician familiar with peptide protocols.
A long plasma half-life of about 144 hours means Nandrolone Decanoate is commonly dosed every few days or weekly rather than daily. Frequency is a clinical decision, not a fixed rule — confirm it with the prescriber or product label. Comparison of apps that keep a schedule like this: https://doseroutine.com/best-dose-tracking-apps
With a plasma half-life near 144 hours, a single missed dose of Nandrolone Decanoate usually has a smaller effect on overall exposure than an irregular pattern of missed doses does. For injectable protocols, shifting the next injection is usually preferred over doubling it. Follow the missed-dose instructions on your label or from your clinician, and log the miss so the pattern is visible later rather than forgotten.
For an injectable like Nandrolone Decanoate the record needs more than a checkbox: vial concentration, the measured volume, and which site the last injection went into. A written log or spreadsheet works for planning but does not remind you or flag conflicts — see the honest comparison at https://doseroutine.com/vs/spreadsheet and the wider roundup at https://doseroutine.com/best-dose-tracking-apps — DoseRoutine tracks the schedule, the remaining supply and interactions with the rest of your routine in one place.
100 mg weekly in the hemodialysis trial; 100-150 mg every 2 weeks in the HIV weight-loss trial. Route reported: Intramuscular. Frequency reported: Weekly to every 2 weeks in those trials. These are amounts documented in the cited studies and labels for Nandrolone Decanoate — they are reported for reference, not a recommendation. Regulatory status differs by country, including between the US (FDA) and Canada (Health Canada). Confirm any amount with a licensed clinician before you take it.
Which studies looked at Nandrolone Decanoate?
Peer-reviewed research indexed in PubMed. Each entry links to the original record.
- 1.Nandrolone Decanoate: Use, Abuse and Side Effects(opens PubMed in a new tab)Medicina (Kaunas) · 2020 · PMID 33187340 · https://pubmed.ncbi.nlm.nih.gov/33187340/
- 2.Nandrolone decanoate: pharmacological properties and therapeutic use in osteoporosis(opens PubMed in a new tab)Clin Rheumatol · 1995 · PMID 8846659 · https://pubmed.ncbi.nlm.nih.gov/8846659/
- 3.The impact of nandrolone decanoate on the central nervous system(opens PubMed in a new tab)Curr Neuropharmacol · 2015 · PMID 26074747 · https://pubmed.ncbi.nlm.nih.gov/26074747/
Sources cited on this page
Specific documents referenced by the numbered markers above. Each number matches the marker in the text.
- PubChem CID 9677(opens in a new tab)National Center for Biotechnology Information · pubchem.ncbi.nlm.nih.gov/compound/9677
Verify at
Publisher search links for Nandrolone Decanoate. These are places to check the information — they are not citations, so they are not numbered.
- Cochrane Library(publisher search, opens in a new tab)Cochrane · publisher search
- DrugBank(publisher search, opens in a new tab)DrugBank Online · publisher search
- Examine.com(publisher search, opens in a new tab)Examine.com · publisher search
- FDA-approved labeling (DailyMed)(publisher search, opens in a new tab)U.S. Food and Drug Administration · publisher search
- Mayo Clinic(publisher search, opens in a new tab)Mayo Clinic · publisher search
- NIH Office of Dietary Supplements(publisher search, opens in a new tab)National Institutes of Health · publisher search
- PubMed literature search(publisher search, opens in a new tab)National Library of Medicine · publisher search
- Wikipedia entry(publisher search, opens in a new tab)Wikipedia · publisher search
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician. How we source and review this information.
What is the short answer on Nandrolone Decanoate?
Plain-text summary, safe to quote verbatim:
Nandrolone decanoate is a synthetic anabolic androgenic steroid (AAS) derived from testosterone. It is known by its common brand name, Deca-Durabolin. Research on Nandrolone Decanoate focuses on bone and joint health and muscle and strength. Nandrolone Decanoate is administered by injection rather than orally.
Source: DoseRoutine — https://doseroutine.com/library/nandrolone-decanoate
Nandrolone Decanoate cheat sheet
DoseRoutine cheat sheet · Hormone
Nandrolone Decanoate
Nandrolone decanoate is a synthetic anabolic androgenic steroid (AAS) derived from testosterone. It is known by its common brand name, Deca-Durabolin.
Evidence
Strong
2 human randomized trials and regulatory approval on file.
Studied range
100 mg weekly in the hemodialysis trial; 100-150 mg every 2 weeks in the HIV weight-loss trial
Route
Intramuscular
Frequency studied
Weekly to every 2 weeks in those trials
Half-life
~144 h
Storage
Room temperature, protected from light
Schedule III (US)Prescription only (US)Bone JointMuscle
Key references
- Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: a randomized, controlled trial (2006)
- Effect of nandrolone decanoate therapy on weight and lean body mass in HIV-infected women with weight loss: a randomized, double-blind, placebo-controlled, multicenter trial (2005)
Studied ranges, not dosing advice. Not medical advice — talk to a clinician. doseroutine.com/library/nandrolone-decanoate
Cite this page
Using this in an article, AI answer, or research note? Please attribute:
DoseRoutine. (2026). Nandrolone Decanoate — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/nandrolone-decanoate
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