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supplement

Evening Primrose Oil

Also known as: EPO, gamma-linolenic acid

Evidence: Preliminary · 20%
Half-life
—
Typical timing
evening
Food rule
with food
Default unit
mg

Studied for

Menopause SupportWomen's Longevity

Overview

Supplies gamma-linolenic acid (GLA). Researched for cyclical breast tenderness, skin barrier support and menopausal comfort. Common doses are 1000-3000 mg/day providing roughly 8-10% GLA.

Known interactions

  • Category rule: glp1 × supplement
    Note

    GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.

    Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

Frequently asked

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Evening Primrose Oil — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/evening-primrose-oil
Canonical URL

Related compounds

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Related benefits

Other compounds studied for the same benefits as Evening Primrose Oil.

Menopause Support

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Women's Longevity

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