Sermorelin Dosage Calculator

Sermorelin is typically dosed 200–500 mcg nightly. Enter your vial size and bacteriostatic water volume to convert that into syringe units.

This is a unit converter. It converts an amount you already have into volume and syringe units. It does not tell you what to take, and it is educational only — not medical advice. Confirm every amount with your clinician and your product label.

Example mixes to try the converter

Examples only — not recommended amounts. These fill in a vial size and diluent volume only — never an amount to inject. Enter the dose your clinician gave you yourself.

Vial size (mg)

Total compound in the vial.

BAC water added (mL)

Volume of bacteriostatic water you reconstitute with.

Target dose

Enter your target dose as a number.

Syringe type

U-100 = 100 units per mL (standard). U-40 = 40 units per mL.

Nothing calculated yet

Enter your target dose as a number.

Sermorelin concentration reference (mg/mL)

What each vial size becomes at common bacteriostatic water volumes.

Vial	+ 1 mL	+ 2 mL	+ 3 mL	+ 5 mL
2 mg	2.00 mg/mL	1.00 mg/mL	0.67 mg/mL	0.40 mg/mL
5 mg	5.00 mg/mL	2.50 mg/mL	1.67 mg/mL	1.00 mg/mL
9 mg	9.00 mg/mL	4.50 mg/mL	3.00 mg/mL	1.80 mg/mL
15 mg	15.00 mg/mL	7.50 mg/mL	5.00 mg/mL	3.00 mg/mL

Sermorelin doses reported in research

The figures below are doses reported in published clinical trials or, where no human trials exist, ranges reported anecdotally. They are reference data only. DoseRoutine does not recommend doses — your prescriber decides yours.

Phase	Dose	Frequency	Notes
Common low	100–200 mcg	Nightly	Conservative starting range.
Common standard	200–500 mcg	Nightly	Most compounding-pharmacy protocols sit here.
Timing	—	Bedtime, fasted	Matches the natural overnight GH pulse.
Review	—	At 3–6 months	IGF-1 is the usual monitoring marker.

Reference ranges reported in the literature and in common practice — not a prescription, and not personalized advice.

What trips people up

5 mg + 2.5 mL = 2 mg/mL, so 300 mcg = 15 units on a U-100 syringe.
Sermorelin has a very short half-life (around 10–20 minutes), which is why it is dosed nightly rather than weekly.
It is a GHRH analogue, so it depends on a working pituitary — it will not work like exogenous HGH.
Sermorelin is prescription-only in the US when compounded for human use.

How the math works

Concentration (mg/mL) = vial mg ÷ bacteriostatic water mL.
Volume per dose (mL) = dose mg ÷ concentration.
Syringe units = volume × 100 on a U-100 syringe, or × 40 on a U-40 syringe.
Doses per vial = vial mg ÷ dose mg. Water volume never changes this number.

Sermorelin calculator FAQ

How many units is 300 mcg of sermorelin?

At 2 mg/mL (5 mg vial + 2.5 mL BAC water) it is 0.15 mL = 15 units on a U-100 syringe. At 1 mg/mL it would be 30 units.

How much BAC water for a 5 mg sermorelin vial?

2.5 mL is common and gives 2 mg/mL. Use 5 mL if your dose is 200 mcg or lower and you want a bigger, more readable draw.

When should sermorelin be injected?

At bedtime on an empty stomach. Its short half-life means it works by amplifying the natural nocturnal growth hormone pulse, and food-driven insulin blunts that pulse.

Sermorelin or CJC-1295?

Sermorelin is the shorter-acting original GHRH analogue; CJC-1295 is a modified version with a longer half-life. CJC-1295 with DAC lasts days, which changes the protocol from nightly to weekly.

Sermorelin reference page Check interactions

Educational tool only — not medical advice. Verify every dose with your prescriber and follow sterile technique. See our medical disclaimer.

More free DoseRoutine calculators and dosing references.

Reviewed by the DoseRoutine editorial team. Last reviewed 2026-08-03.

Who maintains this page

The DoseRoutine Editorial Team maintains the compound library and the interaction rule set behind DoseRoutine. We summarize published trials, regulatory documents (FDA, EMA) and company announcements into plain-English updates. Every factual claim on a post is tied to a linked source below.

Posts are written and reviewed by the editorial team, not by a licensed clinician. This is educational reference content — it never recommends an amount for you to take.

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