Vitamin K2 MK-4

Vitamin K2 MK-4, also known as menatetrenone, is a fat-soluble vitamin and one of the forms of Vitamin K2. It is naturally found in certain animal products, such as meat, eggs, and dairy, particularly from grass-fed animals. Unlike Vitamin K1, which is primarily involved in blood clotting, Vitamin K2 forms, including MK-4, are recognized for their roles in calcium metabolism, bone health, and cardiovascular function (NIH ODS). MK-4 is unique among K2 forms due to its shorter side chain and its ability to be endogenously synthesized in some animal tissues from Vitamin K1. However, dietary intake is considered important for optimal levels in humans (Examine.com). Research on MK-4 often focuses on its potential to support bone mineral density, maintain arterial flexibility, and its broader implications for longevity by optimizing various K-dependent proteins in the body (PubChem). It has a relatively short half-life compared to other K2 forms. Supplements containing MK-4 are commonly available, and it is usually recommended to take it with a meal due to its fat-soluble nature.