Thymosin Alpha-1 (TA-1), also known as Zadaxin, is a synthetic peptide corresponding to a naturally occurring fragment of the larger protein prothymosin alpha. It was originally isolated from the thymus gland, a key organ in the immune system responsible for T-cell maturation. TA-1 is involved in modulating immune responses, particularly by influencing T-cell function and differentiation. It has been studied for its potential roles in various conditions, especially those involving immune system dysregulation, infections, and certain cancers. Its primary mode of action revolves around enhancing specific aspects of cellular immunity. TA-1 is not a vitamin, mineral, or supplement in the conventional sense, as it is a biological peptide.
Deep dive
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Known interactions
Category rule: peptide × hormone
Note
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
* PubChem
* DrugBank
* MedlinePlus
* Cochrane Library
* Examine.com
* NIH Office of Dietary Supplements (ODS) - *Note: ODS may not directly cover TA-1 as a supplement, but serves as a general source for medical information.*
* FDA label equivalent for approved drug products (e.g., from countries where it is approved such as Italy, China, etc. for conditions like Hepatitis B.)
* European Medicines Agency (EMA) Summary of Product Characteristics (SmPC) equivalent documents.
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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