Caution

Is Levothyroxine safe with Magnesium Glycinate?

Usually yes, but with one precaution. Levothyroxine and Magnesium Glycinate are flagged "Caution" because divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.

Confidence: Theoretical

The short version

Verdict
Yes, with care — this combination needs a precaution.
Timing
Separate Levothyroxine and Magnesium Glycinate by at least 4 hours. Taking them in the same window is what causes the issue, not taking them on the same day.
What to do
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Full detail, mechanism and cited sources

People also ask

Is Levothyroxine safe with Magnesium Glycinate?

Usually yes, but with one precaution. Levothyroxine and Magnesium Glycinate are flagged "Caution" because divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.

Can you take Levothyroxine and Magnesium Glycinate at the same time of day?

Separate Levothyroxine and Magnesium Glycinate by at least 4 hours. Taking them in the same window is what causes the issue, not taking them on the same day.

What does DoseRoutine rate the Levothyroxine and Magnesium Glycinate combination?

Yes, with care — this combination needs a precaution. Levothyroxine and Magnesium Glycinate can be taken together, but the combination needs a precaution.

What should someone taking Levothyroxine and Magnesium Glycinate do?

Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours. This is educational information, not medical advice — a prescriber who knows the full routine is the one to confirm it.

Before you combine anything

Counterfeit and mis-dosed product is a bigger risk than most pairwise interactions. How to protect yourself when buying and using compounds covers what to check first.

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DoseRoutine is educational and does not diagnose, prescribe, or recommend a dose. Nothing here replaces advice from a prescriber who knows your full routine.

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