Retatrutide Dosage Calculator
This retatrutide calculator performs concentration and volume arithmetic; it does not choose a dose, validate a research product, or establish sterility. Published trial results concern study-supplied retatrutide under clinical supervision, not an unknown powder sold online. Syringe units describe volume, not drug potency.
This is a unit converter. It converts an amount you already have into volume and syringe units. It does not tell you what to take, and it is educational only — not medical advice. Confirm every amount with your clinician and your product label.
Example mixes to try the converter
Examples only — not recommended amounts. These fill in a vial size and diluent volume only — never an amount to inject. Enter the dose your clinician gave you yourself.
Calculator inputs
Total compound in the vial.
Volume of bacteriostatic water you reconstitute with.
Enter your target dose as a number.
U-100 = 100 units per mL (standard). U-40 = 40 units per mL.
- Enter your target dose as a number.
Retatrutide concentration reference (mg/mL)
What each vial size becomes at common bacteriostatic water volumes.
| Vial | + 1 mL | + 2 mL | + 3 mL | + 5 mL |
|---|---|---|---|---|
| 5 mg | 5.00 mg/mL | 2.50 mg/mL | 1.67 mg/mL | 1.00 mg/mL |
| 10 mg | 10.00 mg/mL | 5.00 mg/mL | 3.33 mg/mL | 2.00 mg/mL |
| 15 mg | 15.00 mg/mL | 7.50 mg/mL | 5.00 mg/mL | 3.00 mg/mL |
| 20 mg | 20.00 mg/mL | 10.00 mg/mL | 6.67 mg/mL | 4.00 mg/mL |
| 24 mg | 24.00 mg/mL | 12.00 mg/mL | 8.00 mg/mL | 4.80 mg/mL |
Retatrutide dosing evidence
Investigational — trial doses, not an approved regimen. DoseRoutine performs arithmetic; it does not choose or recommend a dose. Your prescriber decides yours.
| Phase | Dose | Frequency | Notes |
|---|---|---|---|
| Phase 2 starting doses | 1–4 mg | Once weekly | Randomized trial arms used different starts and escalation schedules. |
| Phase 2 target doses | 1–12 mg | Once weekly | Research exposure only; retatrutide is not FDA-approved. |
Sources
- Retatrutide phase 2 obesity trial — New England Journal of Medicine
- ClinicalTrials.gov NCT04881760 — U.S. National Library of Medicine
What trips people up
- Retatrutide is investigational — it is not FDA-approved and no licensed product exists. Dosing figures come from the Phase 2 trial, not a label.
- At 10 mg vial + 2 mL BAC water you get 5 mg/mL, so 1 mg = 20 units on a U-100 syringe. Easy mental math.
- Adding more BAC water does not change the total drug — it only makes each unit smaller and easier to measure accurately.
- A small calculated volume may be below the reliable markings on your device. A mathematical result is not confirmation that a preparation can be measured or administered safely.
How the math works
- Concentration (mg/mL) = vial mg ÷ bacteriostatic water mL.
- Volume per dose (mL) = dose mg ÷ concentration.
- Syringe units = volume × 100 on a U-100 syringe, or × 40 on a U-40 syringe.
- Doses per vial = vial mg ÷ dose mg. Water volume never changes this number.
Retatrutide calculator FAQ
How much BAC water for a 10 mg retatrutide vial?
There is no approved consumer mixing instruction established by this calculator. As arithmetic only, 10 mg divided by 2 mL equals 5 mg/mL. That example does not recommend a diluent, confirm a vial contains retatrutide, or establish a safe dose.
How many units of retatrutide is 2 mg?
It depends entirely on concentration. At 5 mg/mL (10 mg vial + 2 mL), 2 mg = 0.4 mL = 40 units on a U-100 syringe. At 10 mg/mL (10 mg + 1 mL), the same 2 mg is only 20 units.
How long does a reconstituted retatrutide vial last?
This calculator cannot establish stability, sterility, or a beyond-use date. Adding bacteriostatic water does not validate a research vial for 28 days. Study preparations have controlled instructions; a generic online storage rule cannot substitute for product-specific evidence.
Can I skip titration and start at a high dose?
A clinical trial escalation schedule is not a self-treatment protocol. The reported study used supervised enrollment, specified treatment arms, and adverse-event monitoring. This calculator cannot assess eligibility, tolerability, or an appropriate starting amount.
Educational tool only — not medical advice. Verify every dose with your prescriber and follow sterile technique. See our medical disclaimer.
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Reviewed by the DoseRoutine editorial team. Last reviewed .