medication

Naproxen

Also known as: Aleve

Evidence: High · 100%
Chemical structure of Naproxen (PubChem CID 156391)
Structure via PubChem
Half-life
14 h
Typical timing
with_meal
Food rule
with food
Default unit
mg

Studied for

Overview

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to manage pain, inflammation, and fever. It is available over-the-counter (OTC) and by prescription in various strengths. It's often prescribed or recommended for conditions such as arthritis, menstrual cramps, gout, and other types of musculoskeletal pain. Naproxen works by reducing the body's production of certain natural substances that cause inflammation. It is generally taken orally, often with food to minimize stomach upset. Its effects can last for several hours due to its relatively long half-life compared to some other NSAIDs (PubChem).

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

["Cochrane","DrugBank","Examine.com","FDA label","Mayo Clinic","MedlinePlus","NIH ODS","PubChem"]

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Naproxen — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/naproxen
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