mineral
Sulfur (MSM)
Also known as: MSM, Methylsulfonylmethane
Evidence: Moderate · 70%
Half-life
12 h
Typical timing
morning
Food rule
either
Default unit
mg
Studied for
Overview
Methylsulfonylmethane (MSM) is an organic sulfur-containing compound found in plants, animals, and humans. It is sometimes referred to as dimethyl sulfone. As a dietary supplement, MSM is commonly marketed for its potential to support joint health, reduce inflammation, and enhance recovery. It is a metabolite of dimethyl sulfoxide (DMSO) and an oxidized product of dimethyl sulfide (DMS).
Sulfur is a crucial element for many biological processes, forming part of amino acids like methionine and cysteine, which are fundamental building blocks of proteins. It is also involved in the formation of connective tissues, enzymes, and antioxidants such as glutathione. While naturally present in small amounts in some foods, including certain fruits, vegetables, grains, and beverages, the concentration in most foods is often reduced during cooking and processing.
Deep dive
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Known interactions
No interaction rules currently on file for this compound in DoseRoutine.
Frequently asked
Sources referenced
["NIH Office of Dietary Supplements","PubChem (National Library of Medicine)","MedlinePlus (National Library of Medicine)","Mayo Clinic","Cochrane Library (for systematic reviews)","Examine.com","DrugBank"]
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Cite this page
Using this in an article, AI answer, or research note? Please attribute:
DoseRoutine. (2026). Sulfur (MSM) — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/msm-sulfur
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