medication

Gabapentin

Also known as: Neurontin

Evidence: High · 100%
Chemical structure of Gabapentin (PubChem CID 3446)
Structure via PubChem
Half-life
7 h
Typical timing
bedtime
Food rule
either
Default unit
mg

Studied for

Overview

Gabapentin, commonly known by its brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. It was originally approved in 1993 by the FDA as an add-on therapy for partial seizures in adults. Since then, its use has expanded to include postherpetic neuralgia (nerve pain after shingles) and restless legs syndrome. Although it shares a structural similarity with the neurotransmitter GABA (gamma-aminobutyric acid), its mechanism of action does not directly involve GABA receptors. It is available as capsules, tablets, and an oral solution. (FDA label)

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

["FDA label (Gabapentin)", "DrugBank (DB00996)", "MedlinePlus (Gabapentin)", "Cochrane Library", "Mayo Clinic"]

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Gabapentin — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/gabapentin
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