Ecdysterone, also known as 20-hydroxyecdysone, is a naturally occurring ecdysteroid found in insects and certain plants, including spinach and quinoa. Ecdysteroids are a class of steroid hormones that play a role in molting and metamorphosis in arthropods. In plants, they are thought to serve as a defense mechanism against insects. Interest in ecdysterone within the human context stems from early research suggesting potential anabolic effects without the androgenic properties typically associated with steroidal compounds. It is commonly marketed as a dietary supplement for individuals seeking to enhance muscle protein synthesis, improve strength, and support exercise performance. While some preliminary studies indicate Ecdysterone's potential, robust human clinical trials are still emerging. It is available in various supplement forms, often standardized to contain a specific concentration of 20-hydroxyecdysone. It is important to note that Ecdysterone is not an anabolic steroid in the same class as those regulated by athletic organizations or medical bodies for their potent androgenic effects. Regulatory statuses for Ecdysterone can vary depending on the country or sports governing body. Consumers should be aware of these distinctions when considering supplementation.
Deep dive
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Known interactions
Category rule: glp1 × supplement
Note
GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.
Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Frequently asked
Sources referenced
* Examine.com
* PubChem
* World Anti-Doping Agency (WADA)
* National Institutes of Health (NIH) Office of Dietary Supplements (ODS)
* Mayo Clinic
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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