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medication

Vardenafil

Also known as: Levitra

Evidence: High · 100%
Chemical structure of Vardenafil (PubChem CID 135400189)
Structure via PubChem
Half-life
5 h
Typical timing
pre_workout
Food rule
either
Default unit
mg

Studied for

Longevity

Overview

Vardenafil is a medication primarily used for the treatment of erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase-5 (PDE5) inhibitors. The drug works by increasing blood flow to the penis, which helps to achieve and maintain an erection suitable for sexual activity. Vardenafil is available in tablet form and is typically taken orally. While effective for many individuals, it requires sexual stimulation to work. It was initially marketed under the brand name Levitra. (FDA label, DrugBank)

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors lower blood pressure; amantadine can add orthostatic hypotension.

    Rise slowly; monitor BP. Report dizziness or fainting.

Frequently asked

Sources referenced

- Cochrane - DrugBank - Examine.com - FDA label (Vardenafil) - MedlinePlus - PubChem

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Vardenafil — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/vardenafil
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