Prednisone is a synthetic corticosteroid medication, part of a class of drugs known as glucocorticoids. It is chemically similar to cortisol, a natural hormone produced by the adrenal glands. Prednisone works by mimicking the effects of these natural hormones, primarily by reducing inflammation and suppressing the immune system. Once administered, prednisone is converted in the liver to its active form, prednisolone. This conversion is essential for its therapeutic effects. Due to its potent anti-inflammatory and immunosuppressive properties, prednisone is widely used to treat a variety of conditions affecting numerous organ systems. It is available in several forms, most commonly as oral tablets, solutions, or delayed-release capsules, but can also be given intravenously in hospital settings (per DrugBank, NIH MedlinePlus). Its use is typically short-term for acute conditions or as part of a long-term management plan for chronic diseases, always under strict medical supervision due to potential side effects and the need for careful dosage management.
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Known interactions
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Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
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Category rule: vitamin × medication
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Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
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Sources referenced
- DrugBank
- U.S. National Institutes of Health (NIH) MedlinePlus
- Mayo Clinic
- U.S. Food and Drug Administration (FDA) label
- Cochrane Library
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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