medication

Famotidine

Also known as: Pepcid

Evidence: High · 100%
Chemical structure of Famotidine (PubChem CID 5702160)
Structure via PubChem
Half-life
3 h
Typical timing
bedtime
Food rule
either
Default unit
mg

Studied for

Overview

Famotidine is a medication classified as a histamine H2-receptor antagonist, often referred to as an H2 blocker. It works by decreasing the amount of acid produced in the stomach. It is commonly used to treat and prevent various conditions involving excess stomach acid, including heartburn, acid indigestion, gastroesophageal reflux disease (GERD), and ulcers of the stomach and intestines. Famotidine can be obtained over-the-counter (OTC) in lower strengths for self-treatment of occasional heartburn, and in higher strengths by prescription from a healthcare provider for more serious or chronic conditions. It is available in various forms, including tablets and oral suspensions. According to DrugBank, Famotidine was developed by Yamanouchi Pharmaceutical Co. and was first approved for medical use in the United States in 1986. It is commonly known by its brand name, Pepcid.

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

["NIH Office of Dietary Supplements (ODS)", "MedlinePlus (National Library of Medicine)", "PubChem (National Center for Biotechnology Information)", "DrugBank", "FDA label (U.S. Food and Drug Administration)", "Cochrane Library"]

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Famotidine — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/famotidine
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