peptide

Copper Peptide GHK

Also known as: Skin GHK-Cu

Evidence: High · 90%
Half-life
1 h
Typical timing
any
Food rule
either
Default unit
mg

Studied for

Overview

Copper Peptide GHK, also known as GHK-Cu, is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) that readily complexes with copper(II) ions. This copper-peptide complex is found naturally in human plasma, saliva, and urine. Its concentration in the body tends to decrease with age. GHK-Cu has garnered significant attention in the fields of dermatology and cosmeceuticals due to its reported roles in skin regeneration, anti-aging, and wound healing processes. It is often incorporated into topical formulations like serums, creams, and lotions. (PubChem, DrugBank)

Deep dive

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Known interactions

  • Category rule: peptide × hormone
    Note

    Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.

    Track bloodwork with a provider; don't assume combinations are neutral.

Frequently asked

Sources referenced

- PubChem (National Library of Medicine) - DrugBank (University of Alberta, Canada) - NIH Office of Dietary Supplements (ODS) - general reference for dietary compounds - MedlinePlus (National Library of Medicine) - general reference for health information

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

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Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Copper Peptide GHK — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/copper-peptide-ghk
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