Ramipril, often sold under the brand name Altace, is an angiotensin-converting enzyme (ACE) inhibitor. It is a prescription medication primarily used to treat high blood pressure (hypertension), prevent heart attack, stroke, and death in patients at high risk, and improve survival after a heart attack involving heart failure. It also helps manage heart failure and kidney disease in patients with diabetes. Ramipril works by relaxing blood vessels, which lowers blood pressure and improves blood flow. It is typically taken orally. (Mayo Clinic, DrugBank)
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Known interactions
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
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Category rule: vitamin × medication
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Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
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Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.
Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.
Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.
Sources referenced
* Mayo Clinic
* NIH MedlinePlus
* DrugBank
* PubChem
* FDA label
* Cochrane
* Examine.com
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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