medication

Omeprazole (Prilosec)

Also known as: Prilosec

Evidence: High · 91%
Chemical structure of Omeprazole (Prilosec) (PubChem CID 4594)
Structure via PubChem
Half-life
1 h
Typical timing
morning
Food rule
empty stomach
Default unit
mg

Studied for

Overview

Omeprazole is a medication classified as a proton-pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach. Omeprazole is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), heartburn, stomach ulcers, and a rare condition called Zollinger-Ellison syndrome, which involves excessive acid production. It is available as both a prescription and over-the-counter medication, typically in delayed-release capsule or tablet form. The 'Prilosec' brand name often refers to over-the-counter omeprazole formulations (source: MedlinePlus). Its effects are not immediate; it typically takes a few days for the full acid-reducing benefits to become apparent.

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Caution

    Reduced gastric acid impairs levothyroxine absorption.

    Monitor TSH after starting/stopping PPI; dose adjustment may be needed.

Frequently asked

Sources referenced

- NIH MedlinePlus - DrugBank - Mayo Clinic - FDA label (Omeprazole, prescribing information) - Cochrane Library - PubChem

DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Cite this page

Using this in an article, AI answer, or research note? Please attribute:

DoseRoutine. (2026). Omeprazole (Prilosec) — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/omeprazole-prilosec
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