GHK-Cu, also known as copper peptide, is a naturally occurring small copper-binding peptide that has been identified in human plasma, saliva, and urine. It is composed of three amino acids—glycine, histidine, and lysine—bound to a copper (II) ion. First isolated in 1973 by Dr. Loren Pickart, GHK-Cu's presence in the body declines with age, as noted in research published in aging journals. This peptide plays various roles in human physiology, involving tissue remodeling, wound healing processes, and antioxidant defense. Its biological activity is largely attributed to its ability to modulate the expression of numerous genes involved in regenerative and protective pathways. GHK-Cu is often explored for its potential applications in dermatology and tissue repair due to observations from in vitro and in vivo studies. It is typically available in various formulations, including topical creams, serums, and solutions for injection. As a controlled compound, its use, especially in injectable forms, is under the purview of medical professionals.
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Known interactions
Category rule: peptide × hormone
Note
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
["PubChem (National Center for Biotechnology Information)","NIH Office of Dietary Supplements (ODS)","MedlinePlus (National Library of Medicine)","Mayo Clinic","Examine.com","DrugBank"]
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