peptideInjectable
GDF-11
Evidence: High · 90%
Half-life
1 h
Typical timing
any
Food rule
either
Default unit
mcg
Studied for
Overview
Growth Differentiation Factor 11 (GDF-11) is a protein belonging to the transforming growth factor-beta (TGF-$\beta$) superfamily. It plays a crucial role in regulating embryonic development and tissue homeostasis in adults. Originally identified for its role in inhibiting erythrocyte differentiation, GDF-11 gained significant attention in longevity research due to studies suggesting its involvement in reversing age-related decline in various tissues. It is endogenously produced in the body and its levels can fluctuate with age and health status. The research into GDF-11's precise functions and therapeutic potential is ongoing, with both promising findings and areas requiring further clarification.
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Sources referenced
* NIH ODS (National Institutes of Health Office of Dietary Supplements)
* PubChem (National Library of Medicine's compound database)
DoseRoutine compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Cite this page
Using this in an article, AI answer, or research note? Please attribute:
DoseRoutine. (2026). GDF-11 — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/gdf-11
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