Epitalon, also known by its sequence Ala-Glu-Asp-Gly, is a synthetic tetrapeptide that was first synthesized in the Soviet Union by the scientist Vladimir Khavinson. It is a synthetic analog of epithalamin, a natural polypeptide extract from the pineal gland of bovines. Research into Epitalon has primarily focused on its potential roles in aging and longevity.
Epitalon is not approved as a drug by regulatory bodies like the U.S. Food and Drug Administration (FDA) for any medical condition. Its availability is typically in research settings or as a compound for investigational use. As a peptide, it is generally administered via injection, although other routes are explored in research.
Deep dive
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Known interactions
Category rule: peptide × hormone
Note
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
["NIH National Library of Medicine (PubMed - for specific research articles on Khavinson's work and peptide bioregulation)", "PubChem (for chemical information on Epitalon)", "DrugBank (for comparison regarding approved drug status)"]
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DoseRoutine. (2026). Epitalon (Ala-Glu-Asp-Gly) — Overview, Benefits & Side Effects. Retrieved from https://doseroutine.com/library/epitalon-aegg
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